Sentence examples for been linked with development from inspiring English sources

The lipoxygenase pathway in particular has been linked with development and growth of pancreatic adenocarcinoma, whereas inhibitors of this pathway, including LY293111, inhibit growth of the cancer (Hennig et al, 2002; Tong et al, 2002; Ding et al, 2003).

Inflammatory markers, such as CRP and IL-6, and activation of the HPA axis have previously been linked with development of both T2D (11, 36) and DepS (11, 37) and may confound the studied association.

Expression of androgen receptors has been linked with development of castrate resistance 8, and shown to be upregulated by HIF1 α 9. Furthermore, HIF1 α is upregulated in prostate tumors 10, 11 and is a potent defensive mechanism used by tumor cells against oxidative stress or destruction by androgen deprivation, chemotherapy or radiation cytotoxicity 12.

Gestational diabetes mellitus (GDM) is also increasing and is linked with development of T2D in women, and greater risk for T2D in adolescents exposed to GDM.

Sialic acid is linked with development of neural tissues during embryogenesis [16] and quinolate levels in human brain are thought to be involved in the pathogenesis of neurological disorders (MIM: 606248).

Quality assurance during research and development is linked with development progress and by necessity the extent of quality assurance required will change depending on the methods used, making a uniform definition difficult.

Height is linked with development of many adult cancers [ 37- 39], a meta-analysis of 58 studies also suggested that height is positively associated with incident prostate cancer with stronger effect for advance stage and aggressive disease [ 40].

Since suboptimal vitamin D levels are linked with development of hypertension, it could be assumed that vitamin D replacement or normalization would reduce the risk of cardiovascular disease and its effects.

For instance, STAT4 and STAT6 are historically linked with Th1 and Th2 development, respectively, while more recently STAT3 has been linked with the development of Th17 cells and STAT5 with regulatory T cells 44.

Several studies have shown that WAS KO mice develop autoantibodies and their presence has been linked with the development of renal histopathology 7, 41, 42.

Mutations in Msx2 have been linked with the development of the brain, skull, hair follicles and mammary glands in mice.