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Angiogenic growth factors have recently been linked to tissue metabolism.
The almost constant regeneration of these tissues has been linked to tissue specific adult stem cell populations, which when deregulated have been associated with various diseases and cancers [ 32, 33, 34, 35].
It will also be important to investigate whether Crumbs is involved in similar mechanisms that operate in other developmental events in which actomyosin oscillations have been linked to tissue morphogenesis.
Induction of JA-related response has often been linked to tissue damage, and the important roles of JA signalling in defence against bacterial and fungal infections or caterpillar attack are well documented (for reviews [ 2- 4]).
Consistent with this notion, EndMT has been linked to tissue repair in various organs during angiogenesis and vessel branching, when tip cells acquire a mesenchymal phenotype (Gerhardt et al., 2003).
Similar(55)
Pre-transcriptionally, enrichment of sequence-specific elements within C. elegans promoters has been linked to tissue-specific changes in gene expression [ 9- 11], suggesting that these elements, together with trans-acting factors that recognize them, are fundamental for driving the transcriptional programs of unique tissues.
The significance of these studies is that concentrations of plasma uric acid can be related to measures of oxidative stress, which can be linked to tissue aging.
NTS expression is also found in endocrine tumors and is linked to tissue differentiation [9].
Integrins are linked to tissue invasion by hepatocarcinoma cells [9] and play a role in apoptosis [10].
For an example, in case of tuberculous meningitis, increased MMP-9 expression is linked to tissue destruction, a pathological hallmark of inflammatory host immune response [4] [5].
Any alteration in this balance is linked to tissue damage.
More suggestions(19)
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