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Changes in Ubc9 expression have been linked to primary tumors in humans (Moschos et al., 2010).
Progeroid phenotypes resembling Restrictive Dermopathy (RD) have been linked to primary or, more frequently, to secondary laminopathies [ 15].
This toxin has been linked to primary skin and soft-tissue infections such as furuncles and abscesses (1 ).
A number of the highly interconnected genes in these gene networks have previously been linked to primary ovarian insufficiency (POI) and polycystic ovarian disease syndrome (PCOS).
Interestingly, ELK1 has been linked to primary respiratory chain disease: its target genes show large differential expression between muscle cells and fibroblasts of patients [ 37].
As mentioned already, mutations in the URAT-1 gene have been linked to primary gout, and in a Mexican study, a surprisingly high proportion of patients (23%) were found to carry mutations in the URAT-1 gene [ 15].
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Using geochemical methods (ED-XRF) artifacts are linked to primary and secondary source outcrops throughout southwestern Kenya.
The major employers in the Clutha district are linked to primary industries – including a dairy processing plant and freezing works – and for many years they have been forced to bus in workers from the provincial hub of Dunedin, which is over an hour away.
A wide range of psychiatric disorders, in fact, seemed to be linked to primary headache and preexisting mental disorders are likely to increase the risk for the onset of headache [16].
Most (88%) newly diagnosed individuals were linked to primary care within 3 months of diagnosis [36].
This hypothesis is strongly supported by recent clinical reports, showing that PLP mutations in humans can be linked to primary progressive or relapsing-remitting MS [7], [8].
More suggestions(17)
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com