Sentence examples for been linked to pathogenic from inspiring English sources

Mendelian-PD has been linked to pathogenic mutations in SNCA, LRRK2, PARK2, PINK1, DJ1, ATP13A2 and VPS35 [ 8- 16].

This ability to detect and respond to dead cells has recently been linked to pathogenic responses induced after ischaemic stroke and traumatic brain injury [ 61,62].

The miRNAs formed groups with 1st-to-3rd tier associations with genes involved in biological processes and pathways regulating tissue organogenesis and immune response, processes that have been linked to pathogenic mechanisms of biliary atresia [ 2, 5].

Second, the pathogenic effects of CTRC variants are linked to pathogenic CFTR and SPINK variants resulting in multiple defects in regulating intra-pancreatic trypsin.

In this study, we describe new features of human macrophage cell death induced by A. actinomycetemcomitans leukotoxin that that can be linked to pathogenic mechanisms of inflammatory-related diseases.

In summary, our results suggest that the genetic markers identified with multivariate phenotype highLDLhighTG have phenotypic associations with common traits in MS. The common traits in MS, particularly hyperlipidemia, may be linked to pathogenic associations with osteosclerosis and neurodegenerative disorders including AD and PD influenced by pleiotropic genetic factors.

For example we found, together with David Wraith and colleagues, that AEP makes a cleavage in the middle of a well characterised 'self' epitope in myelin basic protein (MBP) that has been linked to the pathogenic T cell response in multiple sclerosis [64].

Numerous diseases have been linked to a common pathogenic process called amyloidosis, whereby proteins or peptides clump together in the brain or body to form toxic soluble oligomers and/or insoluble fibres.

Several other genes were identified that have been linked to virulence or pathogenic potential (Table 4).

All of these are mammal-associated and two of the three (Raccoonpox virus and Volepox virus) have not been linked to any obviously pathogenic disease in animals or humans.

The ability to produce siderophores, like pyochelin and pyoverdine, has been linked to the bacterial pathogenic potential.