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In their new paper, Dr. Sax and Dr. Gaines analyze all of the documented extinctions of vertebrates that have been linked to invasive species.
c-Jun/AP-1 has been linked to invasive properties of aggressive breast cancer.
Pharyngeal colonization by Salmonella species in resource-poor settings has also been linked to invasive disease [ 12].
ZIP10, the closest paralogue to ZIP6 and the only other LIV-1 family member with a PEST site, has also been linked to invasive breast cancer [ 40], but whether ZIP10 is similarly processed is unknown.
The role of c-Jun on angiogenesis in rodents was also described [ 23]. c-Jun/AP-1 has been linked to invasive properties of aggressive breast cancer [ 24- 27].
Because the expression of cell surface carbohydrate structures reactive with VVA and GS-I lectins has been linked to invasive breast cancer and its metastatic potential, we hypothesized that the expression of TACA reactive with these two lectins may define an aggressive phenotype in DCIS.
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How a cell or group of cells alters its behavior is not completely understood — yet more than 90% of cancer-related mortality is linked to invasive and metastatic spread of cancer cells from the primary tumor.
Our study does not support the idea that neutral genetic diversity is linked to invasive potential.
Constitutively activated NF- κB has been linked to its invasive behavior and degree of malignancy.
The epithelial-mesenchymal transition (EMT) has long been linked to the invasive properties of cancer stem cells.
Furthermore, GL261 tumour cells express CXCR4 (CXC chemokine receptor 4), which has been linked to the invasive and migratory properties of GBM (Zagzag et al., 2008).
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