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In melanoma cells this contribution to motility has been linked to expression of β-catenin, and a proportion of MM do express β-catenin [ 29, 32].
Polarized type 1 or type 2 humoral responses in the laboratory mouse have been linked to expression of specific cytokines and thus can be used to provide insight into the type of response generated by infection.
Differences in the active and passive electrophysiological characteristics of interneurons have also been linked to expression of certain proteins.
Upregulation of Myo10 in breast cancer cells has been linked to expression of mutant p53 (Arjonen et al., 2014).
Cellular senescence and animal aging have been linked to expression of markers of activation of the DNA damage response including phosphorylation of histone H2AX (γH2AX) [ 25- 27].
Indeed, amino acid size and complexity has been linked to expression in the invertebrates D. melanogaster, C. elegans and T. castaneum as well as yeast (Akashi 2003; Cutter et al. 2006; Williford and Demuth 2012).
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One finding of the Jarinova et al. study is that the risk allele is linked to expression levels of ANRIL in whole blood cells from healthy human subjects.
This suggests that higher order genome organisation is linked to expression patterns.
Morphological changes may thus be linked to expression of a differentiated phenotype for some inflammatory mediators.
However, in HCP genes differences in gene body methylation were linked to expression.
Local tumor response in the whole cohort was linked to expression of p21CIP/WAF-1 (p < 0.05), but not p53 expression or mutation.
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