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In addition, histone-modifying complexes have also been linked to differentiation [15].
In addition, miR-10 has been linked to differentiation and cancer by regulating multiple target genes (Lund, 2010).
The MYH7B gene has not been previously implicated in hearing loss but has been linked to differentiation of inner ear hair cells [ 22] and shown to control actin networks within neurons [ 23].
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These results on cytokeratin 10 and Ki-67 staining pattern confirms that CTIP2 is linked to differentiation status of the tumor.
EGFR overexpression is linked to differentiation and aggressiveness of the tumors [ 26].
We suggest that this behavior actually reflects personal agency, which is linked to differentiation and individualism.
These data suggest that autophagy is linked to differentiation and apoptosis.
Unexpectedly, they found that many ESC-enriched core transcription factors, including Oct-4, Sox2 and Nanog, were repressed by p53, while p53-activated genes were linked to differentiation.
Overexpression of Ep-CAM is linked to differentiation and cell proliferation (Jordinson et al, 1999), although the molecular mechanism is still poorly understood.
Alesiani et al. [ 12] demonstrated that melanoma population growth reduction was linked to differentiation processes detected by monitoring some specific markers like melanine synthesis.
For example, syncytin, encoded by the env gene of the HERV-W family is linked to differentiation and morphogenesis of the placental tissue and hypothesized to have immunosuppressive function that supports the maternofetal tolerance [ 4, 5].
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