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Depression has been linked to altering the course of infection due to immune function impairment.
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Several genetic disorders and complex diseases have been linked to altered nuclear architecture and function.
Obesity has recently been linked to altered dopaminergic fronto-striatal circuits, thus implying impairments in cognitive domains that rely on its integrity.
Furthermore, striatal dopamine changes have been linked to altered cortical function during cognitive tasks, in line with preclinical evidence that a circuit involving cortical projections to the striatum and midbrain may underlie the striatal dopamine changes.
The silencing effect of polycomb proteins has been linked to altered chromatin environment and Pol II stalling and, recently, it was proposed that a steric hindrance excluding Pol II elongation may mediate polycomb silencing [28].
57– 59 Mutations in pfatp4 have been linked to altered sensitivity to these candidate antimalarials.
Phosphorylation of Bax at several residues has been linked to altered apoptotic function including altered mitochondrial translocation.
Metamorphosis at small size is has been linked to altered fitness traits, including reduced survival and fecundity.
EE has been linked to altered stress responses in some disorders, but ADHD has not been studied.
PFOS has also been linked to altered cholesterol levels in human epidemiological studies (Eriksen et al. 2013).
N. gonorrhoeae isolates with reduced susceptibility to ESCs have been linked to altered penicillin-binding protein, which is encoded by the penA gene.
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