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Restrained eating behaviour has been linked to abnormalities in metabolic and endocrine functions.
Impaired bowel perfusion has been linked to abnormalities in normal physiologic gut mucosal barrier function, resulting in a permissive effect on bacterial translocation.
Recently, a link has been established between peripheral insulin sensitivity and the retinol (vitamin A) metabolism, and insulin resistance in rodents and humans has been linked to abnormalities of the vitamin A signaling pathway [ 4- 6].
Also, a failure to suppress glucagon levels in response to glucose administration as well as peripheral insulin resistance has been linked to abnormalities in pulsatile insulin secretion (29, 36, 37).
Memory deficits that develop during the course of Alzheimer's disease (AD) have been linked to abnormalities in circulating insulin levels and/or defects in insulin signaling pathways (Luchsinger et al. 2004; Rivera et al. 2005; Craft 2007).
Furthermore, although the defining symptoms of ASD, such as deficits in language, social interactions and personal interests are manifested at the highest cognitive levels, the etiology of ASD has been linked to abnormalities in surprisingly fundamental aspects of nervous system functioning and development.
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Movement through the stages can be due to a combination of genetic vulnerability, life stresses, and substance misuse, and each stage may be linked to abnormalities in biomarkers, such as TNF-alpha, BDNF, and 3-nytrotyrosine (Kauer-Sant'Anna et al. 2009).
The disturbances in tumor cell energy metabolism can be linked to abnormalities in the structure and function of the mitochondria.
Other genes are linked to abnormalities in Type I tumors includingβ-catenin, K-ras and DNA-mismatch repair genes [ 7- 10].
Is it a Different Disease?" and statements such as,"...hypertension in black subjects is linked to abnormalities of control of intracellular sodium," in published articles.
Finally, SHFM type-III (MIM #246560) is linked to abnormalities of a genomic region comprising dactylin and several other genes, in mice and man; however, no disease gene has convincingly been demonstrated, as to date (22– 22).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com