The prognostic relevance of hyperinsulinemia in STEMI patients [ 29, 30] and its relationship with coronary flow [ 31] are less well evaluated and acknowledged.
Anxiety disorders are less well evaluated than depressive disorders but prevalence estimates indicate that one in four people experience one type of anxiety disorder in their life.
Compared to glargine and detemir, the insulin analogues aspart, glulisine and lispro are less well evaluated for mitogenic potential; no increased mitogenic action was found in four in vitro studies [ 25, 28, 30, 34] (Table 1).
Although this indicates that the prognostic value of HMG-CoAR is independent of tamoxifen treatment, we prefer not to draw any further conclusions, because this cohort, while providing robust prognostic data, was less well suited for evaluating treatment predictive effects.
Less well evaluated is the role of healthcare factors, such as the role of prescribing physicians.
Some items on the usability questionnaire of the first intervention were less well rated on average in comparison with the rest of the evaluated items.
The methodology for evaluating quality in reviews of prognostic tests is less well developed than that for diagnostic tests.
Positron emission tomography (PET) has been previously shown to be useful in evaluating patients with HNSCC, but its role in locating unknown primaries is less well defined.
