Sentence examples for been less well defined from inspiring English sources

While CD28 is capable of activating both CD80 and CD86, the relative contribution of the interaction and differential effect of these in vivo has been less well defined.

By contrast, the role of the more abundant protein isoform containing these amino acids, WT1 +KTS) has been less well defined, although it has been suggested that WT1 +KTS) functions as an RBP involved in post-transcriptional gene regulation [22], [23].

Previous studies have documented the presence of IGF-II and IGF-IIR mRNA (18, 33, 44), but protein localization has been less well defined.

Although several prognostic factors have been identified for newly diagnosed myeloma, and for patients with relapsed and/or refractory disease [ 10, 11], genetic factors that may influence responses to therapy, especially in the latter setting, have been less well defined.

Although the D-allele of the ACE I/D polymorphism has been associated with diabetic nephropathy in two large meta-analyses of several thousand individuals [ 3, 4], the role of genetic polymorphisms in other components of the RAS in CKD and CHD in people with type 2 diabetes has been less well defined.

Large clinical trials have revealed that renal dysfunction (RD) is a common problem and one of the major negative predictors of survival in patients with acute heart failure (AHF); however, the influence of different degrees of RD on prognosis has been less well defined.

The well-defined fibrillar features of normal stroma are less well defined with the progression of dysplasia.

It is less well defined for generally damped linear systems.

The duties of the state poet laureate are less well defined.

The 1957 and 1968 pandemics had waves, too, though they were less well defined.

The order of the Three Year and Five Year projects is less well defined.