The use of anti-inflammatory and immunomodulatory agents for pandemic influenza control should be largely evaluated in case of antiviral resistance [ 46].
Currently, response is largely evaluated by measuring magnetic resonance contrast and size change, but this approach does not take into account the key biologic steps that precede tumor size reduction.
In humans, the protective role of Tregs against autoimmune disorders has been largely studied evaluating their number and their activity in several diseases, such as type 1 diabetes [ 10], multiple sclerosis [ 11], systemic lupus erythematosus [ 12], rheumatoid arthrithis (RA) [ 13], psoriasis [ 14], and IBD.
The psychometric properties of PROMs used in elective surgical contexts are usually largely evaluated on pre-operative data, making the interpretation of our ceiling effect, skew and internal consistency more demanding.
It's largely about evaluating predictions in a variety of fields, from finance to weather to epidemiology.
When the goal is to increase failure detection, the Average Percentage of Fault Detection (APFD) metric has been largely applied in order to evaluate prioritization techniques.
However, the contribution of simultaneous Cr VI) adsorption processes in aged magnetite has been largely ignored, leaving uncertainties in evaluating the application of in situ Cr remediation technologies for aqueous systems.
Yet this pathway has not been experimentally evaluated and has been largely overlooked when assessing uptake of phthalate esters.
The impact and relevance of this issue have been largely discussed but not yet fully evaluated.
The recent controversy regarding the cardiovascular safety of rosiglitazone seems to have been largely mitigated by the Rosiglitazone Evaluated for Cardiovascular Outcomes and Regulation of Glycaemia in Diabetes (RECORD) study, which failed to demonstrate either harm or benefit.
