Previous research on mental representations in design is scarce, and has been largely based on students or individual experts.
The identification of brain areas has been largely based on finding reliable differences in one or more features related to cellular/subcellular architecture, connectivity, topography, or function (e.g., Felleman and Van Essen 1991).
In the oceans around Tahiti, gravity-based geophysical investigations have been largely based on marine gravity fields from old-generation altimeter missions and shipborne measurements (Calmant and Cazenave 1987; Sichoix and Bonneville 1996).
In the 1940s and 50s, the scientist Sir Alan Cottrell, who has died aged 92, transformed the field of metallurgy, a subject that had previously been largely based on craft experience and scientific observations, into one that was firmly based on sound scientific principles, with predictive capabilities.
Indeed, randomized trials generally have excluded older diabetic patients, in particular the frail ones, and clinical guidance has been largely based on data obtained in younger (adult) opulations, thus making the optimal therapy of T2DM in geriatric patients controversial.
3, 4 The overall prevalence and clinical outcome of such disorders in cancer patients have been largely based on a cohort of studies in patient populations at risk, hospital-based statistics, and retrospective studies in selected groups of patients.
But their decisions have been largely based on consumer concern rather than scientific evidence and legislation.
Brazil focuses on agricultural exports, while India's growth has been largely based on its domestic market.
Until now, estimates of the global urban footprint have been largely based on optical images of the ground.
The Westminster way of doing things has been largely based on a simple equation of scant information and public ignorance.
Nevertheless, understanding this association has been largely based on cross-sectional designs and on juvenile antisocial outcomes.
