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Beyond this there have been large rises in standards of living and huge advances in medicine and our understanding of health more generally.
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More than a third were over the age of 60, but there were large rises in the number of deaths among young adults and schoolchildren.
Still a relatively new university, Bolton is enjoying large rises in applications and a multimillion-pound development programme to match - £8m will be spent in the next two years to move all subjects to the main Deane campus in the centre of town.
5 Factors contributing to the decrease include smoking bans, media campaigns against smoking, higher cigarette taxes and insurance coverage for smoking cessation programmes. 2 6 On the other hand, there has been a large rise in obesity prevalence over the same period.
The national insurance rise kicked in only last weekend, while homeowners are also facing large rises in council tax from this month because of the additional spending obligations that have been heaped on local government.
When the potassium concentration in Hanks' solution was increased to 60 mM (which is known to depolarize the cell by ∼30 mV), there was a large rise in intracellular calcium.
We can say, however, that there was a large rise in the number of people leaving JSA for reasons that were not linked to employment in association with sanctioning.
Across the risk factors there was a large rise in the recording of information about family history of cancer in new patients; though overall FH recording was a little lower in new patients (40.6% compared with 43.0%).
Two of the most salient trends surrounding the issue of migration and development over the last two decades are the large rise in remittances, and an increased flow of skilled migration.
There was a large rise in the number of executions in Iran - at least 317 people, up from 177 - and Saudi Arabia, where the total rose from 39 to at least 143.
Some experts are focusing on the transformation of America's "masculine" manufacturing economy into a "feminine" service and retail economy to explain what they say is a large rise in male status anxiety and asocial behavior, symbolized by the teenage boys who killed 13 people and themselves at Columbine High School last year.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com