Sentence examples for been known to activate from inspiring English sources

Standard chemotherapeutic agents etoposide and cisplatin have been known to activate p53 and we found activation of p53 by miR-128.

One can speculate the involvement of mitogen activated protein kinase (MAPK) cascade since wounding and systemin have been known to activate MAPKs upstream of octadecanoid pathway in tomato plants as well as autotrophic cell cultures [ 4].

Though Ang II has been known to activate the Nuclear Factor-κB (NF-κB) signalling pathway through different receptor subtype(s) in different tissues under various diseases, the subtype orchestrating this stimulation in type 2 diabetic kidney remains elusive.

PTH has long been known to activate osteoclasts, cells of hematopoietic origin formed by the differentiation and fusion of mononuclear monocyte-macrophage lineage precursors that are responsible for bone resorption.

For example, fatty acids have long been known to activate ANT [ 11, 12] and UCPs [ 14, 15], but there is no consensus on how this activation is mediated.

p53 transcriptional activity can only be executed if its interaction with its inhibitor MDM2 (murine double minute 2) is abolished, and AKT-mediated phosphorylation of MDM2 has been known to activate MDM2.

MT-1 MMP is known to activate pro-MMP-2 to its active form, thereby degrading ECM [ 25].

PB, which is known to activate CAR by an indirect mechanism, was not active in this assay.

Over 200 physiological stimuli are known to activate NFκB.

The nACP-containing scaffolds released calcium and phosphate ions which are known to activate osteoblast function.

Furthermore, cytokines are known to activate different signalling pathways such as the MAP kinase signalling cascade [17].