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Prof Peter Donnelly, director of the Wellcome Trust Centre for Human Genetics at the University of Oxford, who co-led the research, said: "It has long been known that human populations differ genetically, but never before have we been able to observe such exquisite and fascinating detail".
It had long been known that human beings physically resemble the primates more closely than any other known living organisms, but at the time it was a daring act to classify human beings within the same framework used for the rest of nature.
For > 60 years it has been known that human exposure to high doses of RDX causes headache, dizziness, vomiting, and confusion, followed by tonic-clonic seizures (Barsotti and Crofti 1949; Kasuske et al. 2009; Kucukardali et al. 2003).
It has long been known that human mt-mRNA can be polyadenylated (3), but even after numerous attempts to determine its exact role, the function of this modification is still unclear.
It has long been known that human breast tumors have low percentage of activating Ras mutations 27, 28 but that does not necessarily mean that Ras plays no role in breast cancer.
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Monkey See, Monkey Do: It's long been known that humans tend to mimic each other's movements (cross your legs and chances are your companion will, too).
It is known that human history in Kenya dates back millions of years, because it is there that some of the earliest fossilized remains of hominids have been discovered.
In addition, it is known that human plasma lipids are much more complex than the sterols examined in the above lipid measurements.
It is known that human IgG1 binds more strongly to NK cells expressing homozygous FcγRIIIa-Val158 than to those expressing FcγRIIIa-Phe158 (Koene et al., 1997; Wu et al., 1997).
It is known that human p53 is inhibited by glutathionylation of cysteine present in the proximal DNA-binding domain during oxidative stress [39].
It is known that human stem cells (hSC) are ultimately involved in numerous crucial biological processes such as embryologic development; maintenance of normal homeostasis; aging; and aging-related pathologies such as cancerogenesis and other diseases.
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Justyna Jupowicz-Kozak
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