Sentence examples for been known that both from inspiring English sources

It has been known that, both in yeast and human, the assembly of K63-linked poly-Ub chains requires Ubc13 and a Uev to form a stable heterodimer ([Hofmann and Pickart 1999]; McKenna et al. [2001]; VanDemark et al. [2001]).

It has been known that both holo TFIIH and core TFIIH are functionally operative in reconstituted dual incision systems, whereas CAK appeared to negatively regulate the in vitro dual incision [5].

For several decades it has been known that both essential and pregnancy-related hypertension are associated with elevated serum levels of antibodies [ 1– 4].

On the other hand it has long been known that both estrogen and progesterone affect mammary gland development regulating ductal elongation, side branching and differentiation.

It has been known that both the structure of the (fluorophore) aglycone and the type of linkage between the (fluorophore) aglycone and xyloside can affect the priming activity of xylosides.

For example, it has long been known that both mitochondria and chloroplasts function through the formation of electrochemical potential gradients.[ 8] These gradients depend on unbalanced transfer of ions between cellular compartments separated by membranes.

For almost 10 years it has been know that both H2S and CO act as vasodilators (Leffler et al., 2006).

It is known that both reduced and oxidized N forms can be beneficial, depending on site-specific edaphic and climatic conditions.

It is known that both Horn formulas and sets of functional dependencies are learnable in the exact model of learning with queries.

It is known that both, pure lead and PbBi, exhibit a high corrosivity against austenitic and ferritic steels, because of the high solubility of nickel and iron in PbBi.

While it is known that both pathogens utilize quorum sensing (QS) to determine their population size, it is not yet clear whether potential bacterial competitors can also use this information.