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NIS expression has been induced in several BC cell lines including MCF7, T47D, and BT474 [ 52].
However, in order to model human disease, organ-specific inflammation has been induced in several organ systems.
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Interestingly, even when arrest is induced in several of these deletion strains, it has been found that they do not undergo normal repair [33], [34].
Members of the AP-1 family of transcription factors, especially c-fos, are induced in several models of neuronal injuries [105], [106].
The 21 amino acid bicyclic peptide, that is constitutively expressed by the endothelium and that can be induced in several other cell types[4], [5], is implicated in several cardiovascular diseases[4], [6], [7], cancers[8] and pain[9].
Similar conclusions were reached in a histological study of the BALB/c mouse spleen during the course of infection with Listeria monocytogenes, where Irga6 (IIGP1) was seen to be induced in several cell types shortly after infection, but no expression was reported before infection [6].
HDAC1 acetylation is induced in several physiological events.
The Nrf2 response has been shown to be induced in several tissues in response to chemical or physiological stress.
We have shown that Trim17 is induced in several models of neuronal apoptosis, both in vitro and in vivo.
COX-2 expression in mammary epithelial cells can be induced in several ways, among others by estrogen receptors (ER) [ 22].
To summarize, high CRP serum levels are induced in several inflammatory conditions and are not specific for atherosclerosis.
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