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Moreover, high histamine biosynthesis and content have been indicated in human tumors including melanoma, lymphoma, leukemia, colon, gynecologic, and breast cancer, as well as in experimental tumors 12– 12.
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A tumour suppressor function for p53 is indicated in human lung cancer and in carcinoma of the colorectum.
Interestingly, the association between an increased production and or bioavailability of IFN-α and alterations in DC homeostasis has been indicated in various human inflammatory and autoimmune diseases.
This implies that NFTs are important for hippocampal neurodegeneration, as has been indicated in studies of human AD [ 30].
Increased MMP activity has been indicated in both animal and human studies of heart failure with ventricular dilatation and fibrosis [ 19, 21, 26, 27].
A protective role flavonoids in the diet of humans has been indicated in some large prospective studies.
The total number of up-regulated genes or over-represented GO-terms for each compartment is indicated in the first column (human) and the first line (murine) of each panel.
A much longer modal interval would be expected of cycling around an MCA infarct in humans than is indicated in Fig. 6.
Human seasonal H1N1 and H3N2 strains isolated in a specific time period were indicated in brown and blue, respectively; other human strains were left in green and strains isolated from other hosts were left achromatic.
Cell types and biological functions are indicated in green in Drosophila (left) and human (right).
The sites of immunoevasion activities of human herpesviruses are indicated in Figure 8. Several herpesviruses modulate the earliest steps of MHC I biogenesis and trafficking in the secretory pathway.
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