In recent years, preclinical and clinical development strategies have evolved so that agents are increasingly selected for further development based on mechanisms of action rather than relying on historical epidemiological observations.
Improvements in the timing of ART initiation have contributed to mortality reductions in PLHIV on ART, but also among those who have not (yet) started treatment because they are increasingly selected for early stage disease.
Pop music is being increasingly selected by currently serving politicians, notably by the three main party leaders.
In recent years, rendering facilities are increasingly selecting biofiltration for combating nuisance odor.
Fliers are increasingly selecting seats as soon as they book their flight.
However, students are increasingly selecting other routes, ordering from photo centers or making their own.
Peptides are increasingly being selected for drug development because they are specific for their targets and have a higher degree of interactions.
And what are selectees being selected for?
Indeed, senators from Nevada, Montana, New Mexico and Colorado recently sent a letter to Howard Dean, the Democratic Party chairman, urging him to select Denver as a way of increasing the party's chances of winning several Western states that have been increasingly up for grabs.
Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is increasingly advocated for selected patients with CPM; however, opinions are divided because of the perceived lack of evidence, high morbidity, mortality, and associated costs for this approach.
