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Detection frequency of major QTL with varying degree of linkage disequilibrium (r) between the QTL and closest linked SNP marker estimated in the total panel for which missing genotyping-by-sequencing like array data have been imputed with four algorithms (Beagle, FImpute, IMPUTE2 and Random Forest) based on four different missing rates (72.8%, 61.5%, 38.8%, and 16.1%).
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Missing data were imputed with multiple imputation procedures using NORM, version 2, software (32).
Missing data will be imputed with multiple imputation techniques [ 56, 57].
Missing covariate data were imputed with multiple imputation using IVEwareE [ 16].
If there are many missing data, the missing data will be imputed with multiple imputation techniques.
Missing covariate values were imputed with multiple imputation by chained equations.
25 Zip code data were missing in 4.3% of the sample and were imputed with single imputation.
Missing values for the confounding factors (BMI, smoking status, and alcohol intake) were imputed with multiple imputation with the ICE programs in Stata.
Missing values were imputed with multiple imputation, conforming with current guidelines, since missing values occurred on various predictor variables (see Supplementary Appendix 1) (Donders et al, 2006).
To perform analyses according to the principle of intention-to-treat, missing observations at follow-up on the outcome measure were imputed with multiple imputation techniques.
These missing covariates were imputed with a multiple imputation model.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com