The results can be implicated to increase the competition in game design to foster the help-seeking and supportive social behavior.
In this regard, inhibition of RNA Polymerase II has been implicated as resulting in activation of the p53 tumor suppressor [ 59, 60], which is known to induce tumor regression [ 61].
A central deficit in cholinergic activity has also been implicated by results showing increased anticholinesterase activity in the brain during endotoxemia [ 54].
These differences may reflect different disease triggers between children and adults, but whilst various viral and other environmental triggers have been implicated, results are so far conflicting.
In addition, EIF2AK2 has been shown to be activated in AD brain[ 27, 28] and has been implicated in neuronal apoptosis resulting from toxic β-amyloid peptides[ 28].
Number of anchors placed has also been implicated, with many failures resulting from fewer than three anchors [16, 24, 29].
In summary, these results indicate that loss of three of the final four group IIA introns for which matK has been implicated in splicing has resulted in relaxed or even positive selection for some codons within domain X in C. nitida.
Polymorphisms in APE1 have been implicated in susceptibility to cancer; however, results from the published studies remained inconclusive.
Since cytokines and growth factors are known to generate ROS which act as secondary messenger, and AR has been implicated in ROS-mediated inflammation resulting in the lung pathology [26], [27].
Neuroinflammatory processes associated with induction of cyclooxygenase (COX) have been implicated in the deleterious events resulting in neurodegeneration.
