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Golden2-like (GLK) gene family members encode nuclear transcription factors that have been implicated to regulate chloroplast development in Arabidopsis, Zea mays, and the moss Physcomitrella patens (Rossini et al. 2001).
However, BDNF has also been implicated to regulate synaptic plasticity [69], and such a plasticity-regulatory action in the early post-ischemic reperfusion period (first 24hr) could help maintain synaptic connections following the ischemic insult, which also could facilitate preservation of cognitive function.
MicroRNA mir143 expression has recently been implicated to regulate ERK5 expression (Clape et al, 2009).
MicroRNA (miRNA) mir143 expression has recently been implicated to regulate ERK5 expression (Clape et al, 2009; Ramsay et al, 2011).
12 Moreover, proteases with distinct function and localization at the neuronal synapses have been implicated to regulate homeostasis at the nerve terminals.
Although condensin has also been implicated to regulate higher-order chromosome structure during interphase, studies on condensin perturbation reveal that aberration occurs predominantly during chromosomal condensation and mitotic progression.
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The G-quadruplexes located in the P1 promoter of B-cell lymphoma-2 (Bcl-2) gene are implicated to regulate Bcl-2 expression.
The heart is an organ where local formation of Ang II is implicated to regulate cardiac remodeling due to increased afterload or ischemia.
In addition to repair mechanisms, also signals regulating cell death and survival pathways were implicated to regulate temozolomide response (Bredel et al, 2006).
Targeting Shelterin protein components may be more effective that targeting telomerase [ 45], especially POT1 which is implicated to regulate telomere length and capping [ 4, 34].
Via the use of molecular approaches, genes cloned from the rice qLTG3-1 and Sdr4 and the wheat QPhs.ocs-3A1 (TaMFT) QTL were implicated to regulate dormancy or low-temperature germination in embryos (Fujino et al. 2008; Sugimoto et al. 2010; Nakamura et al. 2011).
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