Instead of looking for cancerous or precancerous cells, it looks for evidence of certain strains of the human papilloma virus, H.P.V., a sexually transmitted virus that has been implicated in virtually all cases of cervical cancer.
RhoA has been implicated in virtually all stages of cancer progression.
RhoA has been implicated in virtually all stages of cancer progression: for example, in vitro, constitutively active RhoA can stimulate transformation [ 115].
Preposterously, Congress has done nothing to discourage student abuse of alcohol, which is implicated in virtually all college rapes, deadly hazing and disabling and fatal accidents.
The emergent interest in cancer epigenetics stems from the fact that epigenetic modifications are implicated in virtually every step of tumorigenesis.
O-GlcNAcylation is implicated in virtually all cellular processes examined, for instance gene expression (Comer and Hart, 1999), protein turnover (Hart et al, 2007), and also in regulating cellular responses to insulin (Vosseller et al, 2002; Copeland et al, 2008), cell-cycle control (Slawson et al, 2005), stress protection (Zachara et al, 2004) and calcium cycling (Clark et al, 2003).
Ca2+ is a common second messenger in the cell that has been implicated in the regulation of virtually all aspects of cellular life, including cell growth, differentiation, motility and death (Clapham, 2007; Berridge, 2012).
Endothelin-1 (ET-1) has been implicated in the pathogenesis of multiple disorders involving virtually every organ system, including congestive heart failure, pulmonary artery hypertension, atherosclerosis, cancer, autoimmune diseases, chronic kidney disease, and others [ 1].
Mutations in virtually all of the proteins comprising the cardiac muscle sarcomere have been implicated in causing Familial Hypertrophic Cardiomyopathy (FHC).
Virtually every immune cell type and inflammatory mediator has been implicated in the disease process at one time or another.
