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To the Editor: Fresh produce increasingly has been implicated in viral disease outbreaks (1 ).
NRIP interacts with the androgen receptor [ 39] and has recently been implicated in viral replication [ 40].
Apoptosis, the major form of programmed cell death, has been implicated in viral disease progression and pathogenesis of many viruses.
These ATPases have been implicated in viral life cycle functions such as DNA entry into the host, and viral genome packaging into preformed procapsids.
IAV nucleoprotein (NP) has also been implicated in viral pathogenesis and host range determination; however, there has been no report of its direct role in influenza virus-induced cell death.
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It has been proposed that PABP cleavage, together with hydrolysis of other RNA-binding proteins, such as polypyrimidine tract-binding protein (PTB) and other PABP-associated proteins, are implicated in viral RNA switching from translation to replication [58], [60], [61], [62].
Of note is a G/A polymorphism at position 6413 which changes Ala to Thr and restores the "CETTG" motif which is implicated in viral fusion activity [ 72].
Substitutions V234M and R222Q buffer deficiencies in neuraminidase folding or stability caused by H275Y and simultaneously allow the virus to keep its neuraminidase/hemagglutinin balance, which is implicated in viral fitness (19 ).
Using the BMPV-GFP construct as a marker of susceptibility, we found that phenotypic segregation of the 77 RILS derived from a cross between BAT93 and JaloEEP558 [ 29] fitted a 1 1 ratio, suggesting that a single gene may be implicated in viral resistance.
Humoral responses against extra-cellular HIV-1 Tat may be beneficial as Tat has been implicated in the viral pathogenesis associated with HIV-1 disease progression.
Tat-SF1 has been implicated in both viral transcription and splicing, as well as in general elongation [63] [65].
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