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The small guanosine triphosphatase RhoA/Rho-kinase cascade has been implicated in uterine contraction.
Binding of liganded ERβ to Sp1 sites has been shown in cells expressing endogenous levels of ERβ (Vivar et al., 2010), and Sp1 has previously been implicated in uterine cell-specific expression of the HOXA10 gene in response to estrogen (Martin et al., 2007).
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It is also known that opioid analgesics administered during labor in the form of epidural analgesia are implicated in uterine atony [ 20, 21].
CtGF has been implicated in matrix production during the menstrual cycle, uterine cell growth, implantation, development and differentiation of the embryo, extracellular matrix (ECM) synthesis and angiogenesis.
Mediator complex subunit 12 had not been implicated in human tumorigenesis before identification of specific exon 2 mutations in uterine leiomyomas.
ADAM10 is a transmembrane protein involved in proteolysis and cell adhesion, and has been implicated in the pathogenesis or progression of several cancers, including uterine, ovarian, gastric and colorectal cancer [ 26].
Fusion of placental villous cytotrophoblasts with the overlying syncytiotrophoblast is essential for the maintenance of successful pregnancy, and disturbances in this process have been implicated in pathological conditions such as pre-eclampsia and intra-uterine growth retardation.
Alterations of PRKG1 have been implicated in the origin of clonal expansion of primary tumors from breast cancers [52], hepatocellular carcinomas [53] and uterine leiomyomas [54].
McDowell has been implicated in that dispute.
Several have been implicated in corruption allegations.
Calcium signaling has been implicated in plant graviperception.
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