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Additionally, NMs have been implicated in the protection of plants against oxidative stress as they mimic the role of antioxidative enzymes such as superoxide dismutase (SOD), catalase (CAT) and peroxidase (POX).
Various neurotrophic factors, such as brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and glial cell line-derived neurotrophic factor (GDNF) have been implicated in the protection of neurons against neurotoxins (7- 9).
The ability of activated Ras and Raf to induce autocrine expression of epidermal-like growth factors has been implicated in the protection of MCF10A mammary epithelial cells from anoikis [ 16].
Interestingly, these same pathways have been implicated in the protection of hearts by ischaemic preconditioning [ 52], which is known to prevent the loss of HK2 binding to mitochondria during ischaemia [ 50].
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The protein SGOL1 is implicated in the protection of centromeric sister chromatid cohesion during early mitosis mainly by recruiting PP2A to the centromeric region of chromosomes.
Interestingly, γδTCR+ T cells have been implicated in the protection against breast cancer in women.
HL is an important determinant of plasma HDL cholesterol levels, and is implicated in the protection against development of premature atherosclerosis by HDL [ 21].
The effects of estrogens may be more widespread, however, as it has been implicated in the maintenance of neuronal architecture and protection from free radicals.
Microbiota is critical for human health since it has been implicated in the development of immune system, energy homeostasis, and protection against pathogens.
They play an important role in the protection of epithelial cells and have been implicated in the process of epithelial renewal and differentiation [2], [3].
ERK signaling has been implicated in the proliferation, survival, and protection against receptor-mediated apoptosis of endothelial cells [ 23].
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