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Both the wound and developmental signal JA and the abiotic stress hormone ABA have been implicated in suppression of plant defences during P. syringae infection [32] [36].
Type I IFNs, IFN-α and IFN-β, have also been implicated in suppression of bone resorption.
CD8+ regulatory cells have also been implicated in suppression of fetal immune rejection from early pregnancy in mice (Clark et al., 1994; Blois et al., 2004a).
A separate preparation of this material was analysed by Western immunoblotting with anti-FasL antibody, since it has been implicated in suppression of CD3- ζ, induction of T-cell apoptosis and exhibits molecular weight forms at these molecular weights.
It is noted that IFN-γ also has tolerogenic effects; it could upregulate Foxp3 expression in CD4+ Treg cells, and has been implicated in suppression mediated by CD8+ Treg cells [ 45– 45].
As PRC components, such as Bmi1, have been implicated in suppression of p19ARF expression, it is possible that Mysm1 acts as part of a bigger complex regulating sequential deubiquitination and ubiquitination of the p19 ARF promoter during different phases of thymocyte development.
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The GR-like LXXLL motif is implicated in suppression of IL-12 production in monocytes[19].
ER stress in insulinoma cells was shown to impair insulin signaling through activation of ATF3, an ER stress response protein that was implicated in suppression of IRS2 expression [14].
One key molecule highly expressed by Treg cells that is implicated in suppression of GC responses is CTLA-4 [ 61].
Collectively, these results suggest that Pol κ is implicated in suppression of ssDNA after recovery from replicative stress in human cells.
It is a negative regulator of TLR signaling cascade and was implicated in suppression of the TLR2 [ 12] and TLR4 pathways [ 14].
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