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Hippocampal α-Ca2+/calmodulin-dependent protein kinase II (α-CaMKII) has been implicated in spatial learning, neuronal plasticity, epilepsy, and cerebral ischemia.
The hippocampus has long been implicated in spatial memory, from work in rodents to imaging and brain lesion studies in humans.
Candidate regions for this second stage to the process of VSI are therefore the posterior parietal cortex, which has been implicated in spatial processing [17] [21] and visual feature binding [22], and the occipito-temporal cortex, which is thought to underlie global integration of local signals [23] [25] and the perception of subjective / virtual contours [26] [29].
Whereas the dorsal hippocampus has been implicated in spatial memory processes, the ventral hippocampus may play a role in anxiety.
Similarly, the mPFC has been implicated in spatial temporal order memory but not spatial object recognition (Hannesson, Vacca, Howland, & Phillips, 2004).
Based on gene family classification of the Arabidopsis ortholog At5g42630, this transcription factor belongs to the KANADI family of transcription factors, which has been implicated in spatial arrangement of phloem, cambium, and xylem [ 33].
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As we can see, the hippocampus, an area that is well known to be implicated in spatial memory, is activated during the learning task the first day of training.
We also identified in autism a second key system in the precuneus/superior parietal lobule region with reduced functional connectivity, which is implicated in spatial functions including of oneself, and of the spatial environment.
Lastly, as the avian hippocampus is implicated in spatial memory and in synthesizing multimodal cues, we tested whether the hippocampus was involved in initiating nest building after recognizing a reproductive context [21,22].
Adult hippocampal neurogenesis, which is represented by DCX+ and DCX/BrdU+ cells in the dentate gyrus, is closely related to hippocampal plasticity and is implicated in spatial memory formation and processing [ 11, 12].
We have identified a third key system in the precuneus/superior parietal lobule (including paracentral lobule) region with reduced functional connectivity which is implicated in spatial functions including of oneself, and of the spatial environment, and have suggested that this provides an important contribution to theory of mind processing, which is impaired in autism.
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