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This is the first time NFIB has been implicated in small cell lung cancer, though it has been seen in a mouse study of prostate cancer.
Moreover, hfq has been implicated in small RNA regulation of mRNAs [42], [44], efficient translation of the sigma-factor encoding rpoS [45], [46], and, most recently, interference with mRNA binding to the 30S ribosomal subunit [47], the same ribosomal subunit to which aminoglycosides bind [23], [48], [49].
Ebola virus has also been implicated in small chains of transmission among persons with direct contact with intermediary hosts, mostly nonhuman primates in the central African countries of Gabon and Republic of the Congo.
A possible confounding factor, however, is that these patients were frequently on immunosuppressive agents that have been implicated in small bowel damage (Gabe et al., 1998, Bjarnason et al., 2004, Bjarnason et al., 2006), although if this was the case then this should have been equally evident in PSC as they were receiving the same drugs.
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PI3K p110δ has been implicated in smaller litter sizes in a previous study using knockout mice on a 129 background (Li et al., 2013).
This phenomenon has been implicated in chemorefractory small cell lung cancer and resistance to targeted therapies5,6,7,8, but remains incompletely defined.
Myo1b has also been implicated in non-small-cell lung cancers (Ohmura et al., 2015).
Our results suggest that the most likely source of this outbreak was the same dairy goat farm, Farm A, as had been implicated in a smaller outbreak in the area the previous year.
Besides these ligands are correlated with breast cancer, DBGP/DARC has aroused the interest in cancer research as it has been implicated in non-small cell lung cancer tumorigenesis (NSCLC) [ 10], prostate cancer incidence [ 11, 12], and breast cancer development [ 13].
"Produce has been implicated in a very small percentage of food-borne illness outbreaks," the association said in a position paper, "and most of these were caused by improper handling, not by farm practices".
Several factors have been implicated in the loading of small RNAs into Ago proteins (programming) and the maturation of RISC in human cells.
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