Sentence examples for been implicated in significant from inspiring English sources

However, treatment with ASNase has been implicated in significant reduction of plasma levels of the coagulation serine protease inhibitor (serpin) antithrombin III (AT3), predisposing patients to thromboembolic complications.

The Department of Justice is often criticized for failing to prosecute the C.E.O.s when banks or major corporations are implicated in significant wrongdoing.

The most likely explanation for the ready attribution of these illnesses to cyanobacterial LPS lies in the realisation that LPS from Gram-negative heterotrophic bacteria are implicated in significant morbidity – and mortality – so cyanobacteria, which are widely but somewhat inaccurately accepted as Gram-negative bacteria may equally be responsible for illness because they contain LPS.

Deletions of one or more exons in the mismatch repair genes MLH1 and MSH2 have been implicated in a significant fraction of hereditary nonpolyposis colorectal cancer (HNPCC or Lynch syndrome).

By the beginning of the new millennium, Hh signaling had been implicated in a significant number of cancers, including lung, prostate and pancreatic [ 28] as well as BCC and medullobalstoma, the most prevalent and recalcitrant form of brain tumor in children [ 29].

Frontalis hypertonicity has long been implicated in patients with significant dermatochalasia or blepharoptosis, as evidenced by eyebrow changes that occur after the resection of redundant skin or after blepharoptosis operation.

Aberrant expression of specific receptor tyrosine kinases (RTKs) has been implicated in the genesis of a significant proportion of sporadic human breast cancers.

Moreover, the VHL gene has also been implicated in the development of a significant proportion of sporadic clear cell kidney cancers (Gnarra et al, 1994).

But it was a surprise, he says, that cats and dust mites, which had been implicated in other areas, did not appear significant.

Although ADAM10 has been implicated in Notch and β-catenin signaling, no significant changes in the respective target genes were observed in adult ADAM10 transgenic mice.

This is significant as these neurons have already been implicated in the ability of the worm to initiate backward motion.