BCL-2 promotes cellular survival [ 30] and may be implicated in satellite cell growth and survival.
Recently, interleukin-6 (IL-6) has been implicated in muscle stem cell (satellite cell -mediated muscell -mediatedy in animusclehypertrophye role of in-6 in the sanimalse cell (SC) response following muscle-lengthoweverconthections in humans has not been studied.
More recently, Sprouty1 has been implicated in controlling quiescence of adult satellite cells [ 32], although it is not notably modulated in vivo in comparisons with activated satellite cells [ 31].
Although centriolar satellites have been implicated in protein trafficking in relation to the centrosome and cilium, the details of their function and composition remain unknown.
Multiple age-specific differences in the niche of satellite cells have been implicated in the decline of old muscle repair, however, relatively little is known about the role of altered inflammatory response in the aging of tissue regeneration either in general or in skeletal muscle.
Interestingly, hepatocyte growth factor signaling has also been implicated in myoblast chemotaxis [15] suggesting a link between satellite cell activation and cellular motility.
In insects, both satellite sequences and TEs have been implicated in genome size variation (Vieira et al. 1999, 2002; Kidwell 2002; Bosco et al. 2007).
FHL3 also plays a role in myogenic progenitor cells (satellite cells), where it localizes to the nucleus and has been implicated in the regulation of proliferation [ 45] and differentiation [ 46].
Furthermore, gap junctions on satellite cells surrounding the somata of sensory neurons have also been implicated in the spread of aberrant excitation within the DRG (Zhang et al., 2009).
CCL2 has been implicated in promoting breast cancer metastasis [ 74] as well as prostate cancer growth [ 75] while TREM1 expression in hepatic satellite cells negatively correlated with disease outcome and its expression was related to aggressive tumor behavior [ 76].
