Sentence examples for been implicated in replication from inspiring English sources

Human ACF has been implicated in replication of heterochromatin during S-phase, and RNAi-mediated depletion causes a delay in cell cycle progression through late S-phase [13].

Homologous recombination-based mechanisms have been implicated in replication re-initiation at sites of collapsed replication forks and double strand breaks.

This coincides with the location of a tRNA gene, a feature that has previously been implicated in replication termination.

However, in certain mammalian cell lines, fork reversal has been implicated in replication restart mechanisms under conditions causing replication stress (Berti et al., 2013; Zellweger et al., 2015).

A distant homolog of the Whirlies, the TIF1 protein from the protist Tetrahymena thermophyla has been implicated in replication of DNA as well as in the faithful intergenerational transmission of genetic information and is required for activation of an intra-S-phase checkpoint triggered by DNA-damage [ 32- 34].

XRCC1 and PARP-1-containing complexes have also been implicated in replication-associated repair, a process that is critical for preventing the incorporation of damaged bases into the DNA.

Homolog of Afd1 encodes protein associated with the cohesion complex, which establishes sister chromatid cohesion [ 33- 35], while RPA70 is implicated in replication, repair, and transcription [ 36].

Very recently, Rpd3L-C proteins were implicated in replication timing events in yeast [ 52], so a plausible explanation for epistasis between these complexes could be based on the coordination of DNA replication or the regulation of gene expression or both.

The composition skew may be extended to include a number of oligomer sequences, which are known to be or are likely to be implicated in replication, recombination, and/or repair process of genomes [ 13, 14].

The association between integrins and tetraspanins is common within cells [ 30] and it has been implicated in adenoviral replication and internalization [ 31, 32] allowing Adenoviral replication even in cell lines lacking adenovirus receptor [ 33].

In addition to their role at sites of damaged DNA, MRN and other members of the intra-S phase checkpoint response have been implicated in normal replication initiation events at origins and during re-initiation at sites of stalled or collapsed replication forks [38].