Sentence examples for been implicated in primary from inspiring English sources

Tooth loss or periodontal disease is associated with systemic endothelial dysfunction, which has been implicated in primary open-angle glaucoma (POAG).

We have recently proposed this pro-angiogenic protein as a target for mesothelioma treatment[7] DNA repair overexpression has recently been implicated in primary tumours with subsequent high metastatic potential, e.g. melanoma[42], and proteasome function interacts closely with some repair mechanisms [60], [61](Table 5).

The WRAP53 gene has moreover been implicated in primary human cancers.

MMPs have been implicated in primary and metastatic tumor growth and angiogenesis, and may even contribute to tumor promotion.

Increased circulating level of the cytokine interferon alpha (IFNα) is a stable, heritable trait in SLE which has been implicated in primary disease pathogenesis.

The damage caused by ROS has also been implicated in primary open angle glaucoma (POGA), which is the leading cause of irreversible blindness and the second most common cause of all blindness after cataracts.

It is also possible that both are implicated in primary infection.

Previous studies have reported that both CXCR4 and CXCR7 play roles in breast cancer growth and metastasis, with both receptors being implicated in primary tumor growth, invasion and metastasis formation [ 2, 6, 10, 12, 22].

In line with this, the manifestations of these diseases can overlap: organ fibrosis has been shown to drive malignant transformation, and cancer-associated fibrosis and desmoplasia are implicated in primary tumor growth and metastatic dissemination.

In this study we focus on the kinetics of monocyte trafficking in vivo and in particular on the role of CD44 that is implicated in primary adhesive interactions between leukocytes and endothelium and has a major role in leukocyte homing in EAU, as well as CD62L and PSGL-1 that have been shown to account for at least 90% of leukocyte rolling in vivo.

STAT3 and cMyc have also been implicated in both primary tumor growth as well as tumor metastasis [46] [48].