Sentence examples for been implicated in playing from inspiring English sources

The mature enzyme plays a key role in modifying the extracellular matrix and as a result has been implicated in playing a role in the formation of cancer "niches" where tumors will develop and eventually metastasize.

PcG proteins have recently been implicated in playing a major role in genome organization within mouse embryonic stem cells, suggesting that the clustering of polycomb-regulated genes within polycomb bodies may have far-reaching consequences for nuclear architecture and function.

Proteases and reactive oxygen species (ROS) have long been implicated in playing key roles in host tissue injury at sites of inflammation dominated by macrophage activations and/or neutrophil infiltrations.

GPR4, a G-protein coupled receptor, functions as a proton sensor being activated by extracellular acidic pH and has been implicated in playing a key role in acidosis associated with a variety of inflammatory conditions.

The neostriatum (caudate/putamen), in particular, has been implicated in playing a vital role in regulating motivational drive and coordinated movement.

Many growth factors and cytokines such as, hepatocyte growth factor (HGF), insulin-like growth factor-one (IGF-1), IL-4 and leukemia inhibitory factor (LIF), among many others, have been implicated in playing some role in regulating the SC response [15] [20].

Epigenetic mechanisms have been implicated in regulation of genes playing role in parasite virulence, differentiation and cell-cycle control [ 13].

In each of these capacities, HSP27 has been implicated in different disease states playing both protective and counter-protective roles.

Chronic systemic inflammation has been implicated in atherogenesis, and may play a role in destabilizing vulnerable coronary plaques, thereby precipitating acute thrombosis and clinical CV events [ 13].

A role for TCR affinity has not been implicated in these events, but may play a role dependent on whether TCR affinity affects these implicated signaling events.

Because fibrinogen has been implicated in atherothrombosis, it is thought to play a role in PM-mediated CVD.