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Cigarette smoke exposure, a common health issue, has been implicated in oxidative stress and the concomitant cell apoptosis [6], [7].
Lastly, SIRT7 has been implicated in oxidative stress resistance through an investigation of primary cardiomyocytes from SIRT7 knock-out mice.
3 PINK1 has also been implicated in oxidative stress defense, mitophagy, and the regulation of mitochondrial calcium homeostasis.
Regulation of ROS-mediated signaling by Rac1 has been implicated in oxidative stress, transformation, metastasis, and cell survival [ 15].
Antioxidant GSH depletion and changes in the activity of various antioxidant enzymes indicative of lipid peroxidation have been implicated in oxidative damage of cellular macromolecules [ 37].
Fyn kinase, which is said to have key role in promoting Nrf2 degradation, has been implicated in oxidative stress-associated functional insufficiencies as well as apoptosis.
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Rodrigues, C. et al. Rat Aquaporin-5 is pH-gated Induced by phosphorylation and is implicated in oxidative stress.
An ohr mutant has previously been shown to be less resistant to the oxidative stress generated by 20 mM Tertiary-Butylhydroperoxide, suggesting that Ohr may be implicated in oxidative stress resistance in E. faecalis [60].
Angiotensin II-mediated signalling is implicated in oxidative stress, inflammation, and insulin resistance, factors that cause EPC dysfunction.
Angiotensin II-mediated signalling is implicated in oxidative stress and inflammation; it accelerates the onset of EPC senescence via increased oxidative stress [ 16].
However, it has been published that SEPW1 is strictly correlated with p53; in fact, it is implicated in oxidative modifications of p53, and its knockdown induces cell cycle arrest by increasing p53 [ 18].
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