Sentence examples for been implicated in osteoblast from inspiring English sources

CCN5 has been implicated in osteoblast and chondrocyte function [ 28].

BMP2 signaling has been implicated in osteoblast differentiation [ 39].

BMPs have been implicated in osteoblast differentiation (Abzhanov et al., 2007; Bandyopadhyay et al., 2006) and are expressed in fin osteoblasts during regeneration (Smith et al., 2006).

In particular two pathways have been implicated in osteoblast differentiation and bone formation: the bone morphogenetic protein (BMP) signalling pathway, of which several proteins induce ectopic bone formation [ 4], and the wingless-type (WNT) signalling pathway [ 5].

cthrc1 has been implicated in increased osteoblast proliferation and higher bone mass; in isolated osteoblasts from cthrc1-null mice, alkaline phosphatase, collagen type 1α1 and osteocalcin expression levels were reduced [36].

Wnt signaling has been implicated in both promoting osteoblast [45] and attenuating osteoclast function [23].

P38 is constitutively activated in human myeloma and has been implicated in osteoclast and osteoblast activity and bone destruction [ 229].

On a physiological level, GCs have been implicated in the regulation of chondrogenesis and osteoblast differentiation, as well as maintaining homeostasis in cartilage and bone.

Although a number of transcription factors including cAMP response element binding protein (CREB) [18], [19], AP1 family members [20] [22], and Runx2 [23], [23] have been implicated in the molecular actions of PTH in osteoblasts, genetic studies have not strongly linked any of these factors in the anabolic actions of this hormone.

Interestingly, osteoclasts and osteoblasts have been implicated in the maintenance of dormant leukemic clones in the marrow [ 17], which may also be the case for breast cancer.

Low shear flows and IFs have been implicated in inducing proliferation in many normal cells including osteoblasts, 55 adipose-derived stem cells, 56 and endothelial cells.