Sentence examples for been implicated in oncogenic from inspiring English sources

Moreover, its mammalian orthologue Cripto1 has also been implicated in oncogenic signaling pathways.

Abnormal regulation of eIF4E has been implicated in oncogenic transformation.

Moreover, Tiam1 and Rac have been implicated in oncogenic transformation of cells.

It inhibits protein kinase C ɛ and Src kinase activities, both of which have been implicated in oncogenic signaling [ 21].

Amplification of the HER-2 gene leads to overexpression of the receptor, which has been implicated in oncogenic transformation and tumour genesis.

PTP family members are signalling molecules that regulate many cellular processes, including cell growth, and have been implicated in oncogenic transformation.

NF-κB is a crucial factor that is implicated in oncogenic pathways and also regulates immunoinflam-matory responses.

MiR-144 has been implicated in both oncogenic or tumor suppressor roles in different tumors [ 32– 34], but its role in CCA is not yet clarified.

DICER1 is an enzyme responsible for the cleavage of miRNA precursors and has previously been implicated in the oncogenic process of several cancers [ 31– 31].

Mutations involving residues 59, 63, 116, 117 and 119 have also been implicated in the oncogenic activation by Ras protein [ 12].

While the EGFR signaling cascade is essential for homeostasis, dysregulation of EGFR kinase activity has been implicated in the oncogenic transformation of cells [ 3, 4].