Sentence examples for been implicated in normal from inspiring English sources
The gene codes for a protein called RbAp48 that regulates gene expression in a part of the hippocampus, called the dentate gyrus, which has been implicated in normal memory loss.
CKII-mediated phosphorylation of L1 at Ser1181 has been implicated in normal endocytotic trafficking of L1 [13].
Accumulation of AGEs has been implicated in normal aging and in the pathogenesis of diabetes-associated complications and PD.
Some components of these pathways have been implicated in normal development and pathology of the ChP [20] [24].
For example, immune molecules have been implicated in normal developmental synaptic pruning and inhibition of synapse formation following neuronal injury [45].
In addition to their role at sites of damaged DNA, MRN and other members of the intra-S phase checkpoint response have been implicated in normal replication initiation events at origins and during re-initiation at sites of stalled or collapsed replication forks [38].
Among tissues, C-MYB is most prevalent in bone marrow and is critical to generation of definitive hematopoietic stem cells [4]; whereas, A-MYB is abundant in testes and is implicated in normal spermatogenesis and in mammary gland proliferation [5].
Mitochondrial dysfunction is implicated in normal as well as pathological aging, especially in many neurodegenerative diseases such as Alzheimer's disease, Huntington's disease, Amiotrophic Lateral Sclerosis and PD [1], [2], [3].
MiRNAs are implicated in normal biological functioning, including development, differentiation, homeostasis and apoptotic cell death [ 1].
Wnt/ β-catenin signaling is implicated in normal osteoblast differentiation and aberrant Wnt/ β-catenin signaling disrupts normal bone development 6 and is frequently observed in OS 27.
