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Recently a new neurotransmitter system, the hypocretin orexin system, has been implicated in neurological diseases.
Disruptions in migration have been implicated in neurological disorders such as epilepsy, mental retardation, schizophrenia, and dyslexia [1], [2], [3].
Deletions in this gene have been implicated in neurological disorders including autism and mental retardation in anecdotal fashion [1] [4].
miRNA-targeting of the 3′UTR of MECP2 has also been implicated in neurological dysfunction.
More importantly, many Dock proteins have been implicated in neurological diseases or associated with disease-related molecules.
However, arginase also can increase the formation of polyamines, which have been implicated in neurological disease conditions such as Alzheimer's disease and Parkinson's disease.
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Marine ladder-shaped polyether toxins are implicated in neurological symptoms of fish-borne food poisonings.
Apart from cancer-related roles, SRPX2 is implicated in neurological disorders.
Methyl mercury (MeHg), an important environmental toxicant is implicated in neurological disorders such as Hunter-Russell syndrome and Autism.
Four herbal remedies which are either traditionally reported to be used in the treatment of neurological disorders or which are implicated in neurological disorders were selected for investigation.
In 2013, Cheng and colleagues reported that 361 genes were differentially expressed in the brains of G72 transgenic mice, some of which were implicated in neurological or psychological disorders [ 18].
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