Some research suggests the microbiota may also be implicated in neurologic conditions.
Abnormalities in the serotonin transporter (SERT) have been implicated in several neurologic and psychiatric disorders [1,2].
MAO-A dysfunction has been implicated in several neurologic illnesses such as Parkinson's disease, Alzheimer's disease, and Huntington's disease, as well as in psychiatric diseases such as major depressive disorder [3].
Mechanical instability, encroachment on the canal by the involved vertebrae, and coexistent spinal cord malformations have all been implicated in CDS-related neurologic deficit.
Inorganic arsenic, a known human carcinogen, has also been implicated in gastrointestinal, dermatologic, neurologic, reproductive, and cardiovascular effects in humans.
Recently, the VRK family has been implicated in different types of neurologic diseases.
Tremorgens have been implicated in a number of neurologic diseases of cattle collectively known as staggers syndromes, and pose significant agricultural and health problems for both cattle and humans.
Persistent organic pollutants (POPs) have been implicated in myriad human health problems, including cancer, neurologic, immunologic, and reproductive defects, among many other adverse health effects.
PON1 has been implicated in the etiology of a number of adult-onset neurologic diseases such as Parkinson and Alzheimer diseases (Erlich et al. 2006; Leduc and Poirier 2008; Paragh et al. 2002; Zintzaras and Hadjigeorgiou 2004).
In addition, ingestion of As through drinking water has been implicated in several noncancer diseases, for example, peripheral vascular disease; hypertension; respiratory, neurologic, and liver disorders; and diabetes mellitus [ IARC 2004; National Research Council NRCC) 2001; WHO/IPCS (International Programme on Chemical Safety) 2001].
