Sentence examples for been implicated in negative from inspiring English sources

In addition to Bim, the nuclear receptor Nur77 family members have also been implicated in negative selection.

Use of herbicides to suppress herbaceous and woody plant species that compete with planted seedlings has been implicated in negative impacts.

Consistent with this finding, WT and Cic null CD4+ thymocytes exhibited a comparable induction of Nur77, which has been implicated in negative selection through its ability to convert BCL2 into a proapoptotic molecule44,45, in response to TCR stimulation (Supplementary Fig. 8c). Figure 4: Spontaneous induction of TFH cell differentiation and GC response in T-cell-specific Cic null mice.

Moreover, in this study, Nck has been implicated in negative modulation of TCR surface expression [ 57].

Although the CDK8/SRB10 sub-module has been implicated in negative regulation of transcription by phosphorylation of TFIIH, leading to the inhibition of the TFIIH CTD kinase and transcription [ 46], the exact mechanism still is unclear.

MiR-146 has previously been implicated in negative feed-back regulation of these pathways [ 11, 26], similar to a number of signalling proteins, including the protein-tyrosine phosphatase Ptpn6 [ 53, 54].

Atf3 regulates the expression of downstream genes and is implicated in negative feedback regulation of other immediate early genes.

The tyrosine phosphatase SHP-1 (Src homology phosphatase-1) is implicated in negative signaling by a variety of receptors in hematopoietic cells.

JH is required for normal oogenesis and is implicated in negative regulation of adult longevity [ 29], however we observed little overlap in the genes regulated by JH and mifepristone.

Planted tree rows (shelterbelts) in prairie landscapes are a prominent feature and have been implicated in propagating negative edge effects on breeding birds, perhaps through harboring a diverse suite of nest predators.

Sprouty and Spred proteins have been implicated in the negative regulation of ERK signaling after stimulation by FGF [6], [19].