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And the few markers, the genes and the neural networks, that have been implicated in mental disorders do not map well onto the D.S.M.'s categories.
Emotion regulation (ER), broadly defined, has been implicated in mental health, including major depressive disorder (MDD).
A widespread cortical network has been implicated in mental rotation.
The cIPS/PPC has been implicated in mental rotation [61], [62], the processing of object orientation during reaching and grasping [19] and orientation discrimination / classification of 2D / 3D shapes, graspable objects and surfaces [19], [20], [49], [48], [63] [65].
Abnormal neuronal plasticity also has also been implicated in mental retardation, and autism [ 2- 5].
A microdeletion on chromosome 2q region involving FMNL2 has previously been implicated in mental retardation (Lybæk et al. 2009), and association and linkage studies have implicated this same chromosomal region with susceptibility to autism (Imgsac. 2001; Maestrini et al. 2009).
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The serotonin receptor 1B gene (htr1B) has been suggested to be implicated in mental disorders in both humans and other species.
Increasing evidence suggests that disrupted temporal organization impairs behavior, cognition, and affect; further, disruption of circadian clock genes impairs sleep wake cycle and social rhythms which may be implicated in mental disorders.
However, increased activation was seen for eyes closed in the multi-modal regions, such as the STS and the inferior parietal sulcus (IPS) that were implicated in mental imagery by others [56].
Individual, family, and system-wide factors were implicated in mental health care utilization during the reentry process.
A second, the dorsolateral (upper and outer-facing) surface of the frontal lobes, has been implicated in ongoing mental computation (including nonmoral reasoning, like deciding whether to get somewhere by plane or train).
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