Sentence examples for been implicated in long term from inspiring English sources

In mammalian central neurons, the release of retrograde signals from the dendrites has been implicated in long term potentiation and synapse growth (Lledo et al., 1998), negative feedback (Magnusson et al., 2008), neuronal development (Fitzsimonds and Poo, 1998) and systemic signaling (Ludwig et al., 2002).

Interestingly all of these have been implicated in long-term stress responses, aging and age-related neurodegenerative disorders.

As a crucial component of the UPR, PERK activation results in phosphorylation and inhibition of eukaryotic initiation factor 2α (eIF2α), a translational factor that controls the initiation step of protein synthesis which has been implicated in long-term synaptic plasticity and memory formation [ 4].

Therefore, we have tested if brief subthreshold events could be implicated in long-term coding.

Furthermore, Pum is also involved in the development and migration of primordial germ cells [20], [21], [22], and it may be implicated in long-term memory formation and neuronal excitability [23], [24], [25].

Also ApLRRTK signals via MAPK and CREB, both of which are implicated in long-term learning-related synaptic plasticity (Kandel 2001).

As CaMKII is implicated in long-term potentiation (LTP), D-ribose-induced activation of CaMKII may influence LTP of cells.

Mercury is one of the potential environmental xenobiotic toxicants that is implicated in long-term neurological and developmental disorders in both animals and humans [ 1, 2].

In particular these molecules control cell fate and differentiation of neural stem and progenitor cells during development; due to their neurotrophic and regenerative actions they crucially affect injury-induced neurogenesis, neuronal survival and regeneration; moreover, these molecules can also influence neuronal activity and are implicated in long-term potentiation (LTP; reviewed in [ 2]).

Although such persistent activation is implicated in long-lasting synaptic enhancement, it could potentially support also long-term modulation of intrinsic neuronal excitability.

CSPα is a constitutively expressed synaptic vesicle protein bearing a J domain and a cysteine rich "string" region that has been implicated in the long term functional integrity of synaptic transmission and the defense against neurodegeneration.