Sentence examples for been implicated in lifespan from inspiring English sources

Although miRNAs have been implicated in lifespan determination in Caenorhabditis elegans and Drosophila [ 8, 9], little is known regarding their role in phenotypic plasticity.

These genes have recently been implicated in lifespan regulation (Shore & Ruvkun, 2013) and may constitute one of the arms through which RIF has a positive effect on longevity.

CED-4, best known for its role as an activator of the cell-killing caspase CED-3 in programmed cell death, has recently been implicated in lifespan extension by ECT mutants, such as isp-1 (qm150 ) (Yee et al. 2014).

Among the most intriguing molecular factors that have been uncovered are the sirtuins, a family of NAD+-dependent deacetylases that have been implicated in lifespan extension in model organisms ranging from yeast to flies[ 1].

The C. elegans gene pch-2 and its homologs, including TRIP13 in humans, have been studied for their functions in cell mitosis and meiosis, but have never been implicated in lifespan regulation.

Many genes have been implicated in lifespan modulation or DR-related responses; a systematic analysis under additional conditions may provide new insights on their roles in food-dependent responses.

The insulin/IGF-1 DAF-2 receptor pathway is implicated in lifespan control in several species [1].

To explore a possible connection between TOR and Snf1 signaling pathways (because Snf1 takes part in nitrogen signaling and both are implicated in lifespan extension mechanisms), we investigated Snf1 phosphorylation status in the sit4 strain.

SIRT1 (silent information regulator 1) is the mammalian homologue of the yeast Sir2, which is implicated in lifespan extension in model organisms, such as yeast, worms and flies [ 1- 3].

Induction of antioxidant enzymes has been implicated in yeast lifespan extension.

Lipid reserves, quantified in diverse ways, have been implicated in nematode lifespan [ 9- 14] and innate immunity [ 11].