Sentence examples for been implicated in intestinal from inspiring English sources
Signaling via GC-C has been implicated in intestinal epithelial cell cycle regulation, apoptosis, and progression to gastrointestinal cancer [ 13 - 15.
A number of different cytokines have been implicated in intestinal fibrosis and one of the most important of these is TGF-β.
Although PGE 2 has been implicated in intestinal cytoprotection against acute mucosal damage, overproduction or prolonged production of PGE 2 may worsen colitis or induce tumorigenesis, respectively [ 49- 52].
miR-194 has been implicated in intestinal epithelial cell differentiation and maturation [ 54], and our finding of miR-194 expression in stomach of the pig is consistent with this previous report [ 54].
IL-13Rα2 was previously believed to be a decoy receptor, but IL-13 IL-13Rα2 bIL-13 IL-13Rα2o bindingplicated in intestinal fibrogenesis via transforming growthasalsor β (9).
Indeed, Sb has been shown to secrete polyamines that are implicated in intestinal cell maturation, enzyme expression and membrane transport mechanisms [38].
Activation of GC-C by the endogenous ligands guanylin or uroguanylin elevates intracellular cGMP and is implicated in intestinal ion secretion, cell proliferation, apoptosis, intestinal barrier function, as well as the susceptibility of the intestine to inflammation.
Our data suggests that Spo0A exerts significant control over the C. difficile cell envelope architecture and associated structures, several of which are implicated in intestinal adherence, colonisation or subversion of the hosts' immune system.
Besides TNF α, several other cytokines have been implicated in altering intestinal permeability.
A wide diversity of transporters are expressed in enterocytes; however, only a select few have been implicated in the intestinal absorption of drugs.
Intriguingly, in recent studies, GC-C signalling has also been implicated in suppressing intestinal tumourigenesis, suggesting that GC-C agonists might potentially be useful for the prevention or therapy of colorectal cancer.
