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ESAT-6 is a secreted protein of Mtb, which is absent in BCG but has been implicated in inducing protective immunity against Mtb.
The MAGE family consists of related family members that are known to be upregulated in a variety of tumor types[18], but have recently been implicated in inducing transcriptional reprogramming in tumor cells[19].
Many genes and pathways have been implicated in inducing EMT in tumor cells.
Cyclophosphamide has also been implicated in inducing infertility, particularly at doses above 7500 mg m−2.
The FGF pathway has previously been implicated in inducing chondrogenesis in the developing facial prominences (Abzhanov and Tabin, 2004).
In addition, coxsackievirus B, cytomegalovirus, adenovirus, and mumps have been implicated in inducing certain cases of the disease.
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The researchers then used lab rats to understand which hormones were involved, showing that GLP-1 is implicated in inducing alcohol aversion while ghrelin can restore the rats' appetite for alcohol.
In order to determine whether ABA was implicated in inducing the stressed esk1 state, ABA contents were measured in rosettes of wild type and two esk1 mutants (esk1-4 and esk1-5) submitted or not to mild drought (Figure 1) and compared to the ABA-deficient mutant aba3-1, affected in the sulfuration of the molybdenum cofactor required for the last steps of ABA biosynthesis [17], [18].
The PKB/Akt [ 13, 14] signaling pathway is implicated in inducing cardioprotection via an antiapoptotic effect [ 10, 15].
However, compared with the cytokine combination present in SM, the SFs from patients with RA are more efficient at activating neutrophils to express RANK, indicating that factors other than GM-CSF+IL-4+TNF-α are implicated in inducing RANK expression.
To investigate whether these pathways are implicated in inducing β1-integrin expression, MCF-7R cells were treated with TAM alone or with the addition of the signaling pathway inhibitors.
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