In addition, Azospirillum spp. have been implicated in increasing plant resistance to pathogens (Romero et al. 2003; Tortora et al. 2011).
Both Hsp27 and Hsp90 chaperone proteins have been implicated in increasing the activity of the ubiquitin-proteasome system, though they are not direct participants in the process.
Increases in inorganic nutrients are typical on coral reefs influenced by human activities and have been implicated in increasing severity of fungal infections of corals [71].
Additionally, stress activated protein kinases such as AMPK, p38MAPK, JNK, and PI3K have been implicated in increasing VEGFA mRNA stability through their action on the AU rich region of the 3'UTR [40], [41], [42], [43].
The exact role of these proteins is unknown, but in general, these proteins are thought to reside in the cell envelope and have been implicated in increasing antigenic variation [25].
ZO-1 is associated with TJ proteins and the actin cytoskeleton, and is essential for the stability, organization and signaling of TJ proteins; loss or dissociation of the protein from its counterparts has been implicated in increasing barrier permeability [16] [19].
Furthermore, the intermittent hypoxia that is attendant to sleep disordered breathing, has recently been implicated in increased incidence and more adverse prognosis of cancer.
Surgical body suits (space suits), originally designed to reduce the incidence of infection, have paradoxically recently been implicated in increased periprosthetic joint infection rates.
Pesticides have been implicated in increased risk of cardiovascular disease, diabetes, and cancer; so the animals' feed might be linked to these reported adverse effects.
cthrc1 has been implicated in increased osteoblast proliferation and higher bone mass; in isolated osteoblasts from cthrc1-null mice, alkaline phosphatase, collagen type 1α1 and osteocalcin expression levels were reduced [36].
