Sentence examples for been implicated in heritable from inspiring English sources
The large 83.3 Mb region on chromosome 8 encompasses multiple possible breast cancer candidate genes: for example, POLB[ 31] and NBS1 (NBN) [ 32, 33] have previously been implicated in heritable susceptibility to breast cancer; EBAG9 has been suggested to be involved in early stage breast cancer [ 34].
Given that multiplications of SNCA have been implicated in heritable PD, where elevated dosage increases penetrance and lowers age-of-onset, we hypothesized that a subtle increase in SNCA expression over decades confers an elevated risk for late-onset, sporadic PD.
Increased circulating level of the cytokine interferon alpha (IFNα) is a stable, heritable trait in SLE which has been implicated in primary disease pathogenesis.
DNA methylation has been popularly investigated due to its heritable epigenetic modifications of the genome and has been implicated in the regulation of most cellular processes.
Such thrusts would advance our understanding of heritable disorders since mitochondria plays a critical role in maternal inheritance and has been implicated in numerous human diseases.
