Sentence examples for been implicated in eye from inspiring English sources
Interestingly, other lipid-raft molecules have been implicated in eye abnormal ocular development in Drosophila and maintenance of the mammalian central nervous system (29, 30).
In order to characterize new S. mediterranea eye network genes, we analyzed the Smed454 annotated dataset and found a collection of genes, ranging from transcription factors to eye-realizator genes, which have been implicated in eye development in other systems.
The Wnt-PCP pathway is affected by diabetes during pregnancy (Pavlinkova et al., 2009), and it has been implicated in eye development, especially in lens formation (Lee et al., 2006; Chen et al., 2008; Sugiyama et al., 2010; for review, see Poliakov and Wilkinson, 2006), suggesting that abnormal Wnt-PCP signalling might underlie the eye malformations induced by maternal diabetes.
Estrogen receptors, ARs and PRs have been detected in the human lacrimal [ 7, 8] and meibomian glands [ 9] and have been implicated in dry eye [ 10, 11].
Contiguous gene defects involving BMP4 have been implicated in etiology of eye, brain, and digit anomalies (Bakrania, et al., 2008) although carrier first-degree relatives of some of the affected individuals were shown to be phenotypically unaffected.
Recently, dCul1, along with dCul3, has been implicated in development of the eye in Drosophila.
Interleukin-10 (IL-10), although traditionally considered an anti-inflammatory cytokine, has also been implicated in promoting abnormal angiogenesis in the eye and in the pathobiology of autoimmune diseases such as lupus and encephalomyelitis.
Recently, mitochondrial dysfunction has been implicated in corneal cell death related to dry eye disease and keratoconus which contribute to loss of corneal transparency and decreased vision acuity [13], [14].
Because our eyes are particularly attuned to this type of light, it's been implicated in sleep deficiencies and other human health problems.
